Re: Sertraline
Originally Posted by
Frankie123
My problem is it seems to be okay in the morning but in the afternoon for about 4 hours I get terrible physical symptoms which include weakness, lethargy,shaking,racing heart. When the evening arrives I begin to feel better.
Try taking the sertraline in the evening to see if this makes a difference.
Is your anxiety usually worse in the afternoons?
On Monday she wants me to up the dose to 50mg but because of these symptoms I am a bit wary of doing so.
The rule of thumb on this is that side-effects may become worse if the dose is increased before 5 times the half-life of the med which for sertraline is 5 days, but they probably won't be any less if the increase is delayed.
Has anyone else had similar symptoms when starting on this drug.
The symptoms you've described are fairly typical of serotonergic antidepressants (ADs). Serotonin isn't only a brain neurotransmitter. In fact this is one of its lesser roles. It is involved in many functions throughout the body and these can be affected by ADs at the beginning, but the body usually soon adapts with these side-effects then diminishing though they may reappear for a while after dose increases.
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The opinions expressed above are based on my observations and, where applicable, interpretation of cited data and are general in nature. Consult your physician before acting on anything stated.